MATTHEW MCCONAUGHEY – 38 POUNDS
When Matthew McConaughey was cast in the movie Dallas Buyer’s Club, his character was an HIV/AIDS victim. Naturally, such a character would look thin and sickly. While the latter of those could be handled with make up, he needed to also lose quite a bit of weight. Following a regimen of 90% diet and 10% cardio, he managed to lose 38 pounds.
Unfortunately, such drastic and sudden weight loss affected his health as well, having caused his muscles and organs to actually shrink! Thankfully, he gained the weight back once the movie finished filming. Apparently, he was craving a cheeseburger – which is no surprise! With actors putting their health on the line like this for their career, they’ll need to have a sound health insurance policy.